Adjunct Professor of Physics, Ph.D.,Brandeis (1984)
Associate Professor of Neurosurgery

Education

Research Interests

• Reconstruction of vessel lumen, aneurysms, arteriovenous malformations from two or more views
• Determination of position and orientation of objects from a single projection
• Measurement of brain perfusion from single and biplane angiographic images
• Determination of vessel curvature from two or more projections
• Multidimensional analysis of dynamic cardiac angiographic images
• A comprehensive method for determination of vessel sizes in angiographic images

Selected Publications

1. Rudin S, Wang Z, Kyprianou I, Hoffmann K, Wu Y, Meng H, Guterman LR, Nemes B, Bednarek DR, Dmochowski J, Hopkins LN: Measurement of Flow Modification in Phantom Aneurysm Model: Comparison of Coils and a Longitudinally and Axially Asymmetric Stent?Initial Findings. Radiology 231:272-276, 2004.
2. Subramanian N, Kesavadas T, Hoffmann KR. A prototype virtual reality system for preoperative planning of neuro-endovascular interventions. Stud Health Technol Inform. 98:376-81, 2004.
3. Kyprianou IS, Rudin S, Bednarek DR, Hoffmann KR: Generalizing the MTF and DQE to include x-ray scatter and focal spot unsharpness: Application to a new micro-angiographic system. Medical Physics 32: 613-626, 2005.
4. Wang ZJ, Hoffmann KR, Wang Z, Rudin S, Guterman LR, Meng H. Contrast settling in cerebral aneurysm angiography. Phys in Med. Biol. 50: 3171-3181, 2005.
5. Xu J, Xu G, Chen Z, Singh V, Hoffmann KR: Efficient Algorithms for determining 3-D Biplane Imaging Geometry. Journal of Combinatorial Optimization 10(2): 113 - 132, 2005.
6. Dmochowski J, Hoffmann KR, Singh V, Xu J, Nazareth DP. Effects of point configuration on the accuracy in 3D reconstruction from biplane images. Medical Physics 32: 2862-2869, 2005.
7. Divani AA, Qureshi AI, Hoffmann KR, Suri MFK, Kirmani JF. Comparison of asymmetry in cerebral blood flow between brain hemispheres using digital subtraction angiography. J Neuroimaging 16: 139-145, 2005.